This study investigated 24 tablet crushing devices for drug loss using different methods to recover the crushed tablet 24 devices were compared 3 with disposable cups 6 with disposable bags 12
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Paracetamol is the most commonly crushed tablet in hospitals [6 7] most com monly cited as being difficult to swallow [19] and was chosen as the case study medicinal product for comparing tablet splitting devices [20] One paracetamol tablet was weighed and then crushed Three different methods were used to recover the crushed tablet all 24
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Included were splitters screwcap crushers manual grinders and electric grinders Unscored tablets without active ingredient were prepared with a diameter of 9 and 13 mm and a hardness of 100 220 N Tablets were split into two parts and the difference in weight was measured The time needed to pulverise the tablets crush time was recorded
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